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What We Know About Drug Cartels Designated as Terrorist Organizations by the U.S.

In recent years the U.S. government has increasingly treated certain powerful Latin American criminal groups not merely as organized crime syndicates, but as terrorist organizations. That shift reflects both their global reach and the extreme violence they use to retain territory and revenues.

In 2025 President Trump signed a directive instructing the Pentagon to prepare military options against specific cartels and gangs the State Department has labeled foreign terrorist organizations. While details of any military plans remain unclear, and Mexico has rejected the prospect of U.S. troops on its soil, the designations have focused international attention on these groups and on how they finance themselves (Reuters) (El País).

Below we add publicly reported leadership names and the main documented sources of funding for each group.

Sinaloa Cartel

Base: Sinaloa State, Mexico

Reported leadership / status: Long dominated by Joaquín “El Chapo” Guzmán and Ismael “El Mayo” Zambada; El Chapo is serving a U.S. life sentence, and Ismael “El Mayo” Zambada was arrested and extradited to the U.S. and is in federal proceedings as of 2024–2025. U.S. court filings and DOJ statements list Zambada and other senior figures in recent indictments (Department of Justice) (AP News).

Documented funding streams:

Sinaloa Cartel Dominant Areas of Operation

Sinaloa Cartel Dominant Areas of Operation

Jalisco New Generation Cartel (CJNG)

Base: Jalisco State, Mexico

Reported leadership / status: CJNG is widely associated with Nemesio Oseguera Cervantes, “El Mencho,” long described as the cartel’s top leader; other named deputies appear in law-enforcement sanctions and reporting (ACLED). 

Documented funding streams:

Jalisco New Generation Cartel Dominant Areas of Operation

Jalisco New Generation Cartel Dominant Areas of Operation

Cartel del Noreste (CDN) — formerly part of Los Zetas

Base: Nuevo León / northeastern Mexico

Reported leadership / status: U.S. Treasury (OFAC) and Homeland Security actions in 2024–2025 name and sanction specific CDN leaders and arms traffickers; OFAC press releases in 2025 list several high-ranking CDN members by name (U.S. Department of the Treasury).

Documented funding streams:

Northeast Cartel Dominant Areas of Operation

Northeast Cartel Dominant Areas of Operation

Gulf Cartel

Base: Tamaulipas State, Mexico

Reported leadership / status: The Gulf Cartel has been weakened and splintered over the years but remains active; U.S. and Mexican reporting continue to name and prosecute regional leaders (recent captures and removals have been reported by ICE, Reuters and local authorities). Leadership has shifted repeatedly after arrests (ICE).

Documented funding streams:

Gulf Cartel Dominant Areas of Operation

Gulf Cartel Dominant Areas of Operation

La Nueva Familia Michoacana (LNFM)

Base: Michoacán State, Mexico

Reported leadership / status: U.S. indictments and OFAC sanctions in 2024–2025 name co-leaders and senior operatives (including the Hurtado Olascoaga siblings in U.S. indictments) and sanction others tied to the group’s fentanyl production and transnational supply chains. DOJ and Treasury press releases provide names of charged or sanctioned figures (Department of Justice).

Documented funding streams:

 

The New Michoacán Family Dominant Areas of Operation

The New Michoacán Family Dominant Areas of Operation

 

Tren de Aragua

Origin: Venezuela (originated as a prison gang inside the Tocorón prison)

Reported leadership/ status: U.S. Treasury and State Department sanctions identify Héctor Rusthenford Guerrero Flores (a.k.a. “Niño Guerrero”) as the gang’s leader and list other senior affiliates; the State and Treasury Departments have added multiple Tren de Aragua figures to sanctions lists in 2024–2025 (U.S. Department of Treasury). 

Documented funding streams:

MS-13 (Mara Salvatrucha)

Origin: Los Angeles, California in the 1980s by El Salvadoran immigrant

Reported leadership/ status: MS-13 has a decentralized structure. U.S. prosecutions have targeted leaders of the group’s national command (“La Ranfla Nacional”) and named individual coordinators; reporting in 2024–2025 highlights arrests, deportations, and U.S. indictments for senior figures, and court filings suggest continued high-level cooperation and conflict across borders. Journalistic investigations and DOJ filings also discuss jailed leaders who may have negotiated with Salvadoran authorities (U.S. Department of Homeland Security).

Documented funding streams:

The Bigger Picture – What the Designations and Evidence Show

  1. Leaders are being targeted: Since 2024–2025 the U.S. has used sanctions, indictments and extraditions to name and detain or sanction senior figures across these groups — from El Mayo Zambada (Sinaloa) to El Mencho (CJNG affiliates reported) and Héctor “Niño Guerrero” (Tren de Aragua). These actions are documented in DOJ, Treasury/OFAC and State Department releases and in major news outlets (U.S. Department of the Treasury). 
  2. Revenue is diversified and getting darker: While cocaine and heroin trafficking remain core, fentanyl production (and procurement of precursor chemicals), extortion, migrant smuggling, kidnapping, fuel theft, illegal mining, arms trafficking and the abuse of legitimate businesses (real estate, agriculture, concerts/entertainment) are all documented funding streams across different groups. U.S. sanctions and investigative reporting have specifically named many of these revenue channels (El País).
  3. Designations change the tools available to governments: Calling these groups foreign terrorist organizations or Specially Designated Global Terrorists allows the U.S. to freeze assets, sanction facilitators, and criminalize broader support networks — but it also raises legal, diplomatic and operational questions about military options, sovereignty and cooperation with affected countries (Reuters). 

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